Firstly, HP on their website do indicate they are working on a VISTA
version of their Director software which makes sense since it is used
with many of their devices and unlike with printers and scanners they
cannot just say buy a new one!
Secondly, I've never had VISTA refuse to run anything I've installed so
I don't know what is behind that blocking but I just asked HELP about
[program is blocked] and it told me the following:
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Run or remove blocked startup programs
User Account Control prevents programs that require permission or an
administrator password from running automatically when Windows starts.
If a program is blocked, you'll see a message in the notification area
that says some startup programs need permission to run. You can run a
blocked program, remove blocked programs from startup, or ignore the
notification.
To run a blocked program
Right-click the Blocked startup programs icon in the notification area.
Click Run blocked program, and then click the name of the program you
want to run. If you are prompted for an administrator password or
confirmation, type the password or provide confirmation.
Note
You'll need to repeat these steps each time you want to run the program
after starting Windows.
To remove a blocked program from startup
You can remove a blocked program from startup so that it won't try to
run automatically each time you start Windows. Removing the program
from startup won't remove the program from your computer.
Right-click the Blocked startup programs icon in the notification area.
Click Show or remove blocked startup programs.
Notes
If a program that you want to run at startup is being blocked, check
the publisher's website to see if there is an updated version of the
program available that doesn't require permission or an administrator
password to run.
Removing a program from startup might affect other users of this
computer.
See also
What is User Account Control?
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You might want to study this and also look up about Permissions and
Taking ownership. Others here can help you more on this than I can but
I suspect that there is a temporary answer.
For example, you succeeded in installing by using compatibility mode --
have you checked to see if that is inherited by the application itself?
Right mouse click on its exe files and check compatibility -- set it to
XP if it is not already.
Have you checked and extended to the maximum the permissions of the
account you log on with?
Hope some of that helps.