problems with Excel 2007 'system cannot find the file specified'

[sblevins]

My Excel 2007 on Vista has started failing to open documents with the
error 'system cannot find the file specified' when I double click on
an Excel file or Excel attachment. In Outlook, if I double click on an
attachment, 2 copies of Excel open, and 2 copies of the file are
created in my Outlook temporary files folder named file1.xls and
file1(2).xls. File associations are properly set. I cleaned out the
temporary files folder. Help!

Steve Blevins

 

[Ron de Bruin]

It is a good practice not to open files in a mail.
always drag on your desktop before you open it.

But you can try this first to see if you can avoid the error in Excel
Run Office Diagnostics.
Office Button>Excel Options...Resources

Close Outlook/Excel and open Excel again to test it