Yes, you can do this.
However, you need a PDF creator. You can purchase a commercial one form
adobe.
Or you can grab the following free one here:
It is absolutely Free,
And free means no watermarks, no nag screens, no annoying Popup
advertisements, no time limits etc.
It is also very fast, and works very well. I highly recommend it.
http://www.acrosoftware.com/products/cutepdf/Printer.asp
Note that pdf file creators actually install a printer that "CREATES" pdf
files. So, you run your software of choice (Excel, ms-access etc.), and then
print to this PDF creator...and it will then make a pdf file for you.