Windows XP The weirds thing i ever saw..

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Helllo all,

I'm a System Administrator at a company and yesterday i was handing a computer with very strange symptoms.
It started when a guy called me told me he can't open Outlook.exe (0xc0000006 error) and then i started getting more errors from the computer..
Now i can't go into drive C from my computer(My computer>C:) every time i click on the drive icon it shuts down Explorer.exe i can only access the drive if i use the run application.
i keep getting Image Mastering API failures when i re-run Explore.exe
i Tried to remove office from the computer with the original disk and it shuts down the removal process too.

I did a virus scan, everything is normal.
I need help on this one..

OS: XP
Computer: some kind of Dell, 4 years old.
Antivirus: NOD32 , business edition
 
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I would recommend running a scan using Malwarebytes (updated) to see if it detects anything. The second thing which comes to my mind might be the disc playing up here so a disc (and RAM maybe...) diagnostic would be my second shot. It would be good to know the context if anything has been changed recently. IMAPI refers to CD/DVD burning. I'm wondering how the pc behaves in Safe Mode?
 
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PC runs perfect in Safe Mode.
I will try both options when i'll be back in the office on sunday. Thanks for the advices.
 
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in this case sth which loads later messes things up. Assuming that malware have not been found as well as disc errors I would recommend selective startup to try and find the culprit.

Go to msconfig -> Selective startup -> clear Load System Services / Load Startup Services -> apply and reboot.

After the reboot you will get msconfig again. Move to the Services tab and start re-enabling the services. Select one at a time, apply and restart. Move to the Startup tab afterwards. When you start getting problems the most recently selected option should be responsible.
 
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Thanks again for helping.

I did a full restore 6 months back(the only backup that was on the computer) to fix it since the user needed his pc ASAP, but i will consider it next time something like that pop up.
 
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as they always do... :)
System restore is a very good solution if it does help. I've assumed that you'd exhausted the simplier options ;)
 

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