Some virus made change in WINXP SP2 pro

[Sreeraj]

When ever I open any drive (D: or E: etc) its pop ups the 'open with
window'! It is not opening with explorer. Help me to change this...

 

[Malke]

When ever I open any drive (D: or E: etc) its pop ups the 'open with
window'! It is not opening with explorer. Help me to change this...

What makes you think you have a virus? Did you do any systematic scanning?
See this link for steps:

http://www.elephantboycomputers.com/page2.html#Removing_Malware

Otherwise, look for an autorun.inf file at the root of the drives and delete
it.

Malke