yes Go To the following http://www.usa.canon.com/html/conCprDriversTypeSystemV2.jsp
?x=2section=0&t=10001&m=10033&group_id=-
1&type=Software&prodref=PS&subtype=Software&level2catq=AllC
ats&pname=CanoScan%20N650U&modelid=6858#windr vgl2u
Hi Chris,
Yes you can,I am have a Conoscan N650U installed on
winows xp home,I am using the original instalation disc
which came with the scanner,
Bill.
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