For Folders and files:
In Win Exp - Tools, Folder Options, View
Uncheck - Show pop up description ..... etc
if you mean
Disabling Balloon Tips
Go to The Key:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advance
d
Now create a new DWORD value, and name it EnableBalloonTips and set it equal
to 0.
If EnableBalloonTips is already there and equal to 1, set it equal to 0.
Exit the registry editor and then log off and log back on again or reboot.
Balloon tips should now be disabled.
Note you can save the registry key first by:
On the File menu, click Export.
In the File name box, type SaveKey, and then click Save.
Or create a system restore point prior to editing.
Note: If the registry key is not there, you can simply create one by going
edit > new.
http://support.microsoft.com/default.aspx?scid=kb;EN-US;322756
HOW TO: Back Up, Edit, and Restore the Registry in Windows XP
Disclaimer: Modifying the registry can cause serious problems that may
require you to reinstall your operating system. Use the information provided
at your own risk.