Try CCleaner (CrapCleaner) ver 1 38.485 from
http://www.ccleaner.com/download/
The program is free but the fellow is not adverse to accepting donations if
you like his program. It works fine in Vista. Choose your options as you see
fit.
Do not use prior to shutdown. If there are files in the temp folders waiting
to be executed (because you installed new software) they will be deleted.
Run CCleaner after you boot the computer. The files will have then
accomplished what was intended.
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Regards,
Richard Urban MVP
Microsoft Windows Shell/User