subtract column right from column left in excel?

[Muffin]

How do I do entire columns with the same function, like subtraction?
I have excel 2003.

 

[Bernard Liengme]

Question is unclear, please expand on what you want to do
best wishes

 

[Eduardo]

Hi,
if what you mean is each row

=B1-A1

if you mean the whole column

=sum(B1:B60000)-sum(A1:A60000)