If the program is iexploreR.exe and not iexplore.exe then you have a
The is no R in iexplore.exe.
This may be caused by a third-party program (adware, spyware, parasite).
Get AdAware and SpyBot and run them both. Keep them up to date.
Dealing with Unwanted Spyware, Parasites, Toolbars and Search Engines http://mvps.org/winhelp2002/unwanted.htm