I'd first look at any options your ISP might provide you. If there isn't,
you could dig through http://www.slipstick.com and see if there are any add-ons.
If you're comfortable with code, you could build your own working with http://www.outlookcode.com
for assistance.
However, serverside is the best option. If it's client side it only happens
when you download mail and, if I sent someone a message and didn't get a
failed message for 6 hours (because your machine was off), I wouldn't assume
it was because the address didn't actually exist.
Unfortunately, there is no way to do what you want with an email client.
Once your mail host has accepted email for delivery, it is yours; to do with
as you please. The only place where rejection can take place is on the
gateway (MX) server; and, even then, only during the SMTP transaction.
Any particular reason you simply quoted someone else's message?
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