Greetings Louise,
As an alternate, you may like to modify the following registry entry: -
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\UnreadMail
After reaching the above entry, click on the plus sign, this will open
up the list of accounts setup on your computer, click on the account that is
involved in the log on message, in the right portion, double click on
'Message Count' and enter '0' as the value data. This should remove the
message you receive at the log on. Plz remember this is a temporary removal,
as next time if you log on again, and leave unread messages, you will still
receive the error unless you read your mails. So for a permanent solution,
follow Jonathan's post.
Also if you observe, as you click on the above key, you will see a DWORD
value by the name of 'MessageExpiryDays', if you enter 0 or 1 as the value
data, you may still be able to achieve what you want without having to use
the Power Toys.