Eric,
You'll have noticed that everyone is being very cautious about making a real
recommendation as there are a number of side issues involved and other
intricacies involved with your environment that we will not catch from a
newsgroup explanation. Instead, people are trying to give you a handle on
the tools so you can evaluate this appropriately.
To go out on a limb a bit though...
In your circumstance you have an established domain in a relatively large
environment. You don't really have any of the big red flags crying out for
a management domain. Also, the logistics of implementing a management
domain when you are already established are not trivial. This would be a
large project and, while not impossible by any means, probably not worth the
effort.
What you have, though, is a management issue. If you start aggregating
tasks by role and tightening that down you should be able to get a handle on
the Admin issue in just a few months. I know that sounds like a long time,
but it is best to be cautious -- address the big issues immediately but then
really look to restructure your administration with delegations and GPO
controls.
You are at the size where you rally want to pay attention to the MS
recommendations on managing resources with different types of groups. Do
the entire project under the heading of Change Control. Take a look at the
Microsoft Operations Framework and begin the technical and political
implementation of that kind of control. You'll find that your core issue is
not as technical as is it a business issue and Change control is the best
way to get a real handle on it. This will save you in the long run.
Start with these:
MOF Overview --
http://www.microsoft.com/technet/itsolutions/cits/mo/mof/mofeo.mspx
Change Control --
http://www.microsoft.com/technet/itsolutions/cits/mo/smf/smfchgmg.mspx