Mendel said:
I'm scanning somewhere north of 2000 slides. With downsample to
4000dpi (and crop of black edges), they'll JUST about fit on my
(mirrored) 250gig drives. That is 16 bit rgb tiffs. They are
grainy/handheld/mixed quality.
Mendel, if they are grainy images then there is little, if anything,
being gained in saving these as 16-bit per channel. (Assuming that is
what you meant instead of 16-bit 64k colour (ie. 5-6-5 r-g-b) tiff,
since the numbers tie up at 4000ppi 16-bpc with each file around 125Mb).
You may as well half the file size by archiving them in 8-bit per
channel. You will also find that they compress much better as well,
using lossless LZW, when only 8-bit for the very reason that all of that
additional bit depth is just noise - not scanner noise, but noise on the
actual image recorded on film.
I would recommend scanning in 16-bits and then contrast stretching the
image so that the peaks are retained without clipping (so that no useful
image information is lost). Then reduce the bit depth to 8-bits and
save. The Minolta software probably has a function to implement the
stretching with minimum clipping in any case, making this a simple
operation. But if you use Vuescan then the same capability is there and
you can completely avoid the downsampling issue.
I suspect that using this approach you will get more images stored at
full resolution than you will achieve by downsampling and storing at
16-bits per channel, simply due to the improved efficiency of the LZW
algorithm once the noise content has been reduced. It all depends on
how grainy the images are to begin with though.