Unwanted folders installed by Vista

[Guest]

In the root directory of my OS drive there were a number of empy folders
created by something - I assume it was Vista. They all have names like:

2e23bab8965d8884addd8e220128e9

and are empty.

Until I know what they are I'm reluctant to just delete them fearing I'll do
something unexpected to Vista. Anyone know what these are and can I delete
them?

 

[Rogue]

Those are most likely created on the installation of patches as temporary
folders and can be safely deleted. I have deleted the ones on my computer
with no ill effects.

 

[Jupiter Jones [MVP]]

Those are usually temporary files left over from updates.
Reboot the computer and they may be automatically deleted.
Otherwise simply delete them (using an account with Administrator
access).
Sometimes booting to Safe Mode with Administrator access is required.