Peasant said:
Why would you want to? Some games give you that option because
they use fancy cursors that can cause issues but I've never seen
it as an option in Windows. Use standard mouse cursor and you
shouldn't have any issues.
Of course "why" is often a very difficult question to answer. Maybe
another reason might have something to do with dual monitors. In the
homebuilt group, there was recently a complaint about some games not
confining the cursor to the primary monitor, that causes an
occasional exit back to the desktop. Apparently you are talking
about the type of option which is available in Tribes 2, you can
toggle "direct mouse" or something like that and it solves the exit
to desktop problem.