If Motherboard won't POST:
Make sure RAM is seated securely and in correct slot(s) (see manual)
If you're using more than one stick of RAM, try one at a time.
Make sure grafix card seated properly.
Make sure 12 volt supply to motherboard is connected, if required.
Make sure CPU seated correctly (unlikely to be this)
Make sure at least one fan with a speed sensor is connected to CPU fan connector, as Bios may be set to disable if no fan detected.
Reset CMOS (Bios) via jumper (see manual) and try again.
Lastly, try taking out a few Motherboard mounting screws, or all of them, as it's possible there may be a short circuit between board and case. If that doesn't work, isolate motherboard from case using some insulation such as the bag the board came in; a piece of cardboard, something like that. This is unlikely to be the cause, but it's worth a try.
Only have the CPU; RAM & Grafix card connected, disconnect everything else until you've got the thing to POST.
I've probably forgot something, but if that little lot doesn't work, suspect something is faulty.