None. Per Microsoft itself, UAC is the first layer in multilayered
security configuration by removing admin as the typical user, you can
have a 'weak admin' now as standard user.
If you turn it off, you still have the other layers, but each layer is
then labored with having to troubleshoot issues UAC could avoid, i.e.,
installing potential rouge software.
Currently, few full Vista apps exist, and the UAC is invoked in most XP
programs running in Vista, thus annoying. You can turn it off for now
until more full Vista compliant versions are released.
As for now, developers are grasping with what Vista releases have done to
the standard installs. For example of the hassles of installing true
Vista programs, even for seasoned developers, install Adobe Reader 8.0
Vista and watch what happens. To avoid its hassles, try then an install
by invoking XP SP2 compatibility mode, and all the hassles dissappear.
Note even with UAC off, I have had, rarely, a UAC style window appear,
and this is with one Grisoft AVG update. It was not explained anywhere,
since Grisoft was Vista compliant. I later made explicit exceptions for
Grisoft through the Windows firewall and the UAC windows stopped. What a
PITA it was.
http://technet.microsoft.com/en-us/windowsvista/aa905073.aspx#E6B