Assuming you want them to be able to use forms and reports that you've
created in the MDB file, you have no choice but to have MS Access installed.
Fortunately, there is a Developer of Access that you can purchased so that
you can package your application together with a royalty-free run-time
version of Access, so that users who don't have Access can install the
run-time, and use your application.
Tony Toews explains what you need to look for at
http://www.granite.ab.ca/access/developereditionfaq.htm