This one seems to be the culprit:
- - -
Load[0] "" Home-PC\Home *HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\MICROSOFT\WINDOWS NT\CURRENTVERSION\Windows 
- - -
Open Regedit.exe and go to:
HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\MICROSOFT\WINDOWS NT\CURRENTVERSION\Windows 
Backup the branch by exporting it to a REG file.
Delete the value named "Load[0]"
Close Regedit.exe
If that does not help, you may use the freeware Autoruns tool to see if there are any more invalid startup entries.
-- 
Regards,
Ramesh Srinivasan, Microsoft MVP  [Windows Shell/User]
Windows® Troubleshooting 
http://www.winhelponline.com
Here is the sysinfo which you suggested that i post:
Hope it's got the answer.
Thanks in advance
[Startup Programs]
Program Command User Name Location 
OneNote 2007 Screen Clipper and Launcher onenote 2007 screen clipper and 
launcher.lnk Home-PC\Home Startup 
Sidebar c:\program files\windows sidebar\sidebar.exe 
/autorun Home-PC\Home HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
ehTray.exe c:\windows\ehome\ehtray.exe Home-PC\Home HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
WMPNSCFG c:\program files\windows media 
player\wmpnscfg.exe Home-PC\Home HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
Load[0] "" Home-PC\Home *HKU\S-1-5-21-3759801108-965904665-2588745682-1000\SOFTWARE\MICROSOFT\WINDOWS NT\CURRENTVERSION\Windows 
MultiFrame c:\progra~1\asus\asusmu~1\multif~1.exe Public Common Startup 
Windows Defender %programfiles%\windows defender\msascui.exe 
-hide Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
RtHDVCpl rthdvcpl.exe Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
SynTPEnh c:\program 
files\synaptics\syntp\syntpenh.exe Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
DirectMessenger "c:\program files\asus\asus direct 
console\lcmp.exe" Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
PowerForPhone c:\program 
files\powerforphone\powerforphone\powerforphone.exe Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
Symantec PIF AlertEng "c:\program files\common files\symantec 
shared\pif\{b8e1dd85-8582-4c61-b58f-2f227fca9a08}\pifsvc.exe" /a /m 
"c:\program files\common files\symantec 
shared\pif\{b8e1dd85-8582-4c61-b58f-2f227fca9a08}\alerteng.dll" Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
NeroFilterCheck c:\program files\common 
files\ahead\lib\nerocheck.exe Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
GrooveMonitor "c:\program files\microsoft 
office\office12\groovemonitor.exe" Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
SunJavaUpdateSched "c:\program 
files\java\jre1.6.0_01\bin\jusched.exe" Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
avast! c:\progra~1\alwils~1\avast4\ashdisp.exe Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
!AVG Anti-Spyware "c:\program files\grisoft\avg anti-spyware 7.5\avgas.exe" 
/minimized Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
NvSvc rundll32.exe 
c:\windows\system32\nvsvc.dll,nvsvcstart Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
NvMediaCenter rundll32.exe 
c:\windows\system32\nvmctray.dll,nvtaskbarinit Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
ZoneAlarm Client "c:\program files\zone 
labs\zonealarm\zlclient.exe" Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
MSConfig "c:\windows\system32\msconfig.exe" 
/auto Public HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Run 
	
		
			
				Ramesh said:
			
		
	
	
		
		
			Hi Con,
Click Start, type "msinfo32.exe" and press {ENTER}
Navigate to "Software Environment" and select the "Startup Programs" option
From the File menu, choose "Export" and save the listings to a file
Copy the text file contents and include it in your reply.
-- 
Regards,
Ramesh Srinivasan, Microsoft MVP  [Windows Shell/User]
Windows® Troubleshooting 
http://www.winhelponline.com
Hi guys,
I was just wondering whether anyone knows how to rectify the following 
problem.
On starting up windows vista i get an error message with heading "desktop" 
stating the following.
"Could not load or run '""' specified in the registry. Make sure the file 
exists on your computer or remove the reference to it in the registry.
It's not a big problem, but hey who really wants to start a computer and be 
welcomed by an error. lol.
Also the error is correct it does not specify a file that is required, it 
exactly as written above. This error comes up after loading desktop icons, 
but before the sidebar is loaded and system tray programs initialised.
Any help on the above would be greatly appreciated.
Also if the resolution uses regedit or something could you guide me through 
it coz i'm not all that diligent or confident when touching the registry.
Thanks in advance.
Con