You would use the same Excel instance, but drag the right border of Excel to
run into the next display. If it cannot be done with just the graphics
cards, you could download and try the stuff from www.ultramon.com. It will
do it for sure, 'cause I use it to do just that.
I un-maximize the Excel window, and size it across both monitors. Then
un-maximize the document (inner, workbook) windows, and size one to one
monitor, same with the other.