The type of behavior you describe, which also often applies to
Taskmgr.exe and Regedit.exe, is typical behavior of more than one
virus/worm, the three below being the most common:
Because many of the newer viruses and worms, such as the
Spybot mentioned above, can disable antivirus applications whose
definitions aren't kept up-to-date, try using one or more of the free
on-line scanners to double-check your system.
The behavior you describe, which also often applies to
Taskmgr.exe and Regedit.exe, is typical behavior of more than one
virus/worm, the three below being the most common: