Most of the registry changes require a reboot, while it's not necessary in
some cases. Restarting the Shell (explorer.exe process) works in cases. Open
Task Manager and end task Explorer.exe process. Then create a new
Explorer.exe process from File/New. Or, see this from David:
Click Start - Turn Off Computer (or maybe Shutdown) - Ctrl + Alt + Shift +
click Cancel (or Close) (your Desktop and Start Menu now disappear).