Hello Hema,
You should be able to do both ..
Call the compiled exe file of lisp program using
System.diagnostics.process.start()
Keep some delay belay between so that the lisp program executes.
Open the mdb file, read data and do the required processing.
Easiest way could be to perfrom processing in lisp directly...which I
am assuming you don't want to do for some reason.
Hope it helps.