I had Lexmark all-in-one X5260 and an old Epson printer installed on my Vista Business Sony Vaio laptop without problem since early 2008. Yesterday I removed the old Epson, with problems, as it had a test print still in the spooler. Since then I have had â€œSpooler SubSystem Appâ€ problems and been unable to re-install or print from the Lexmark. I did System Restore back to the day before I removed the Epson printer. I carefully removed the Epson printer. Still no printing with Lexmark. I have followed the recommendations of many of the posts here, especially â€œSpooler SubSystem Appâ€ with Alan Morris and Eddie. I uninstalled Lexmark. I followed the procedure recommended in http://members.shaw.ca/bsanders/CleanPrinterDrivers.htm and presumed I deleted the drivers and spoolers. However I was unable to do the â€œnet stop spoolerâ€ and â€œnet stop spoolerâ€. I got the response â€œSystem error 5 has occurred. Access is deniedâ€. In Command Prompt I was not at the root directory, I was at C:\Users\Vaio. (Vaio is my user name.) I am the only user of this laptop and my printer is plugged into a USB port, not networked. I then tried to install from the Lexmark 5200 Series CD. Before getting to the â€œdetecting your printerâ€ phase, I got the Spooler SubSystem App closed error message. Lexmark 5200 now appears in my printers but a test page print or doc print does not work.