selective replies for Outlook messages

I'm somehow concerned, when traveling, that my "out-of-office" message gets
to recipients who might exploit the information inappropriately (paying a
visit to my empty house, for instance).

I'd like to be able to establish a rule where I can select which recipients
Exchange or Outlook will send autoreplies to. Typically, to everybody within
my company and everybody in my contact lists.

Anybody with an answer to this?