Try Method 1 (Remove the registry entry):
http://support.microsoft.com/kb/320553/
"JR" <(E-Mail Removed)> wrote in message
news:41D6D9F2-1C7D-4747-9DA4-(E-Mail Removed)...
>I recently upgraded from XPH to Vista Business. Seems my CDROM.SYS or
>related
> file got corrupted because shortly after upgrading ALL my CD & DVD drives
> stopped working, giving driver errors. Problem is I can't repair Windows
> since there's no DVD drive and when I update drivers or re-install the
> hardware I'm told I have the latest drivers.
> Any suggestions?