Best ways to deploy MSI with GPO

I want to know what is the best way to deploy MSI Package across active
directory domain and GPO !
It's better with computer attribution or user attribution ?

For example, Office 2003 !
What did you do ?

What is the best property in my MSI for deploy with computer assignement ?
If property ALLUSERS=1 and if there isn't advertised shortcut, is it better
to deploy with computer assignement ?

I have a problem with V2i Protector Desktop and Server !
I don't arrive to deploy with GPO !
There is a problem with isscript ?????

What tests did you do before deploy MSI Package with a GPO ?

Thanks for your response !